BPC-157
5 mg
$29.00
MOTS-C is a 16-residue peptide encoded in the mitochondrial 12S rRNA region, supplied as a lyophilized powder vial with a separate vial of bacteriostatic water for reconstitution.
For research and clinical use only. Supplied to licensed practitioners and research professionals. Not evaluated by the FDA.
MOTS-C is a 16-residue peptide encoded in the mitochondrial 12S rRNA region, supplied as a lyophilized powder vial with a separate vial of bacteriostatic water for reconstitution.
Supplied to licensed practitioners and research professionals only. Solubility is pH sensitive — confirm full dissolution before use. Store lyophilized at −20 °C under nitrogen where possible. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.
| Available sizes | 10 mg — $39.00 · 20 mg — $59.00 |
| Form | Lyophilized powder + BAC water vial |
| Molecular weight | 2174.6 g/mol |
| CAS | 1627580-64-6 |
| Sequence length | 16 |
| Storage — sealed | −20 °C, protected from light |
| Storage — reconstituted | 2–8 °C, use within 14 days |
| Ships from | Chicago, IL |
| SKU | PEP-MOTSC |
Research summary — for laboratory and research use only. Not medical advice, not a dosing recommendation, and not an FDA evaluation of safety or efficacy.
MOTS-C was first described in 2015 by Changhan Lee and colleagues at USC, who identified it as a peptide encoded within the mitochondrial genome's 12S rRNA region rather than nuclear DNA — one of a small class of "mitochondrial-derived peptides" discovered over the last two decades.
In the original and subsequent rodent studies, MOTS-C translocates to the nucleus under metabolic-stress conditions and has been reported to activate AMPK signalling, a central regulator of cellular energy balance. This is the basis for its research framing as an "exercise-mimetic" peptide — mouse studies have looked at its effect on glucose uptake and insulin sensitivity under diet-induced metabolic stress.
The core research thread examines MOTS-C's role in the AMPK pathway and downstream effects on glucose handling in rodent models.
Several papers have looked at circulating MOTS-C levels changing with exercise in animal and small human observational studies, prompting interest in exercise-mimetic research designs.
As a mitochondrial-derived peptide, MOTS-C sits within a broader research field examining how mitochondrially encoded signals communicate with the nucleus during aging.
Supplied to licensed practitioners and research professionals only. Solubility is pH sensitive — confirm full dissolution before use. Store lyophilized at −20 °C under nitrogen where possible. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.
No — it's a small peptide encoded in mitochondrial DNA rather than a classical endocrine hormone. It is studied for cell-signalling effects, not sold or intended as a hormone replacement product.
Further reading: for the published preclinical and clinical literature on MOTS-C, search PubMed. We link to the search rather than cherry-picked citations so you can review the current, full body of literature yourself.