BPC-157
5 mg
$29.00
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide modelled on the pineal extract epithalamin, supplied as a lyophilized powder vial with a separate vial of bacteriostatic water.
For research and clinical use only. Supplied to licensed practitioners and research professionals. Not evaluated by the FDA.
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide modelled on the pineal extract epithalamin, supplied as a lyophilized powder vial with a separate vial of bacteriostatic water.
Supplied to licensed practitioners and research professionals only. Highly soluble in aqueous buffer; prepare working solutions fresh. Store lyophilized at −20 °C protected from light. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.
| Available sizes | 10 mg — $39.00 · 50 mg — $99.00 |
| Form | Lyophilized powder + BAC water vial |
| Molecular weight | 390.3 g/mol |
| CAS | 307297-39-8 |
| Sequence length | 4 |
| Storage — sealed | −20 °C, protected from light |
| Storage — reconstituted | 2–8 °C, use within 14 days |
| Ships from | Chicago, IL |
| SKU | PEP-EPI |
Research summary — for laboratory and research use only. Not medical advice, not a dosing recommendation, and not an FDA evaluation of safety or efficacy.
Epitalon (Ala-Glu-Asp-Gly) is a synthetic analogue of epithalamin, a pineal-gland extract studied for several decades by Vladimir Khavinson's group at the St. Petersburg Institute of Bioregulation and Gerontology. Most of the published research on this specific compound originates from that research group and Russian-language gerontology literature; independent Western replication is limited, which is worth weighing when reviewing the claims made about it.
The primary research interest is telomerase activity — early in-vitro and rodent studies from the Khavinson group reported that Epitalon could induce telomerase expression in some cell lines and extend proliferative lifespan in cultured human cells. Proposed downstream effects on pineal melatonin regulation and circadian signalling have also been explored, though the mechanistic picture is far less established than for peptides with a larger independent literature base.
The best-known research thread is in-vitro work on telomerase induction in human somatic cell lines, used as a model for cellular aging.
Because it is modelled on a pineal-derived peptide, some research has examined effects on melatonin regulation and circadian rhythm markers in animal models.
Rodent lifespan studies from the originating research group have been cited in the longevity-research literature, though largely from a single research group's output.
Supplied to licensed practitioners and research professionals only. Highly soluble in aqueous buffer; prepare working solutions fresh. Store lyophilized at −20 °C protected from light. Not evaluated by the FDA and not intended to diagnose, treat, cure or prevent any disease.
It comes primarily from one research group's decades of work; it hasn't been broadly replicated in independent, large-scale studies the way some other peptides have. Treat it as an active research question rather than a settled finding.
Further reading: for the published preclinical and clinical literature on Epitalon, search PubMed. We link to the search rather than cherry-picked citations so you can review the current, full body of literature yourself.